BMP-9

GWB-F5A36D

BMP-9

This product recognises Human BMP9 (Bone Morphogenic Protein) a member of the TGF-beta superfamily. BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins including noggin chordin gremlin and follistatin are responsible for modulating the signaling effects of BMPs through the binding and blocking of receptor ligands thereby preventing activation.

Phosphate buffered saline pH 7. 2

Belongs to the TGF-beta family. Summary: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.