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alpha Tubulin [B-5-1-2]

alpha Tubulin [B-5-1-2]

ArtNr	20-272-190439
Hersteller	GENWAY
Menge	0.1 ml
Kategorie	Oncology Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Immunoassay Primary Antibodies Mikrotubules By Organ Lung Cancer
Typ	Antibody
Applikationen	WB, IF, IP, ICC, RIA
Clon	B-5-1-2
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-75FBD1
Similar products	20-272-190439
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Genway ID:	GWB-75FBD1
Clone:	B-5-1-2
Isotype:	IgG1
Immunogen:	Sarkosyl-resistant filaments from Stronglycentrotus purpuratus (sea urchin).
Positive Control:	Total cell extract of the human foreskin fibroblast cell line (FS11)
Target:	alpha Tubulin
Localization:	Major constituent of microtubules.
Concentration:	2. 3 mg/ml Storage
Preservative:	15mM Sodium Azide; Constituents: 0. 01M PBS. pH 7. 4
Application Note:	ICC: Use at a concentration of 0. 5 - 1 µ g/ml this concentration is recommended using cultured chicken fibroblasts (CFB). IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. WB: Use at a concentration of 0. 25 - 0. 5 µ g/ml this concentration is recommended using a total cell extract of the human foreskin fibroblast cell line (FS11). Predicted
Molecular Weight:	50 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Major constituent of microtubules. Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis intracellular transport flagellar movement and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha tubulin and beta tubulin.
Function:	Tubulin is the major constituent of microtubules. It binds two moles of GTP one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subunit:	Dimer of alpha and beta chains.
Tissue Specificity:	Ubiquitously expressed although primarily in lung and brain.
Ptm:	Undergoes a tyrosination/detyrosination cycle the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL) respectively (By similarity).
Similarity:	Belongs to the tubulin family.

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Menge: 0.1 ml

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Lieferung vsl. bis 25.09.2025

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