alpha Tubulin [TU-01] (FITC)

ArtNr	20-272-191670
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Oncology Antibodies Cell Biology Cytoskeleton Immunohistochemistry Immunofluorescence Primary Antibodies Mikrotubules By Organ Lung Cancer
Typ	Antibody
Applikationen	IF, IHC
Clon	TU-01
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-3975FE
Similar products	20-272-191670
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Genway ID:	GWB-3975FE
Clone:	TU-01
Isotype:	IgG1
Immunogen:	Fraction of tubulin purified from pig brain by two cycles of polymerization-depolymerization.
Antigen Species:	Pig
Target:	alpha Tubulin
Localization:	Cytoplasmic
Conjugation:	FITC
Concentration:	1 mg/ml
Purification Note:	This product purified from pig brain by two cycles of polymerization-depolymerization. This product is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC. Storage
Preservative:	15mM Sodium Azide. Constituents: PBS. pH 7. 4
Application Note:	IF: 1/50. IHC: 1/50. 20-272-191670 works in these applications on fixed and permeabilised cells. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Cytoplasmic Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis intracellular transport flagellar movement and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha tubulin and beta tubulin.
Function:	Tubulin is the major constituent of microtubules. It binds two moles of GTP one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subunit:	Dimer of alpha and beta chains.
Tissue Specificity:	Ubiquitously expressed although primarily in lung and brain.
Ptm:	Undergoes a tyrosination/detyrosination cycle the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL) respectively (By similarity).
Similarity:	Belongs to the tubulin family.

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Menge: 0.1 mg

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