IgG1 [YNB46.1.8]

GWB-EEA635

IgG1

Negative Control

IgG1

From tissue culture supernatant Storage

For FACS: Use at an assay dependent dilution. Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * It is recommended that the user dilutes the antibody for use in their own system to a concentration equivalent to their test antibody. For IHC-Fr and ELISA: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. Myeloma: Spleen cells from immunised PVG-RT1u rat were fused with cells of the rat Y3/Ag1. 2. 3 myeloma cell line CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (\" helper/inducer\" T cells) and is also expressed at a lower level on monocytes tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. This antibody blocks syncytia formation of U937 cells infected with HIV.

Chromosomal aberrations involving IGHG1 may be a cause of multiple myeloma [MIM:254500]. Translocation t(11; 14)(q13; q32) with CCND1; translocation t(4; 14)(p16. 3; q32. 3) with FGFR3; translocation t(6; 14)(p25; q32) with IRF4.

Nie also differs in the amidation states of 35 116 198 269 and 272.

KOL also differs in the amidation states of residues 198 267 and 272.