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Vimentin [SP20] (ready-to-use)

Vimentin [SP20] (ready-to-use)

ArtNr	20-272-194050
Hersteller	GENWAY
Menge	6 ml
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development Antibodies Cell Biology Cytoskeleton Immunohistochemistry Primary Antibodies Intermediate filaments By Organ Lymphatic System Cancer Stem Cell Markers
Typ	Antibody
Applikationen	IHC
Clon	SP20
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-18C49D
Similar products	20-272-194050
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Genway ID:	GWB-18C49D
Clone:	SP20
Isotype:	IgG
Immunogen:	Recombinant human vimentin protein.
Specificity:	This antibody recognizes vimentin. Vimentin is the main intermediate filament protein in mesenchymal cells and is therefore of value in the differential diagnosis of undifferentiated neoplasms. This antibody crossreacts with Human.
Positive Control:	Sarcomas
Target:	Vimentin
Localization:	Cytoplasmic
Concentration:	ready-to-use
Application Note:	We suggest an incubation period of 30 minutes at room temperature. However depending upon the fixation conditions and the staining system employed optimal incubation should be determined by the user. No pretreatment is required for formalin fixed paraffin tissue sections. Cellular
Localization:	Cytoplasmic
Function:	Vimentins are class-III intermediate filaments found in various non-epithelial cells especially mesenchymal cells.
Subunit:	Homopolymer. Component of a complex composed at least of ACTB AP2M1 AP2A1 AP2A2 MEGF10 and VIM. Interacts with HCV core protein.
Tissue Specificity:	Highly expressed in fibroblasts some expression in T- and B-lymphocytes and little or no expression in Burkitt\' s lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
Ptm:	One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division at which time vimentin filaments are significantly reorganized.
Similarity:	Belongs to the intermediate filament family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 6 ml

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