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Myeloperoxidase

Myeloperoxidase

Hersteller	GENWAY
Kategorie	Oncology Antibodies Cell Biology Cell Status Cell Metabolism ELISA Oxidative Stress Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Specific against	other
Clon	19G8
Applikationen	ELISA
Menge	1 mg
ArtNr	20-511-240421
eClass 6.1	32160702
eClass 9.0	32160702
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Genway ID:	GWB-47FD60
Isotype:	IgG1
Clone:	19G8Host Animal: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Immunogen:	Purified human MPO
Specificity:	Myeloperoxidase
Type of Product:	Monoclonal Antibodies to Cardiac Markers
Concentration:	5. 9mg/ml (Sigma protein assay kit)Preservatives: NaN3
Buffer:	PBS. pH 7. 4Applications Notes : Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Recommended pair for sandwich immunoassay:. Capture Detection. 20-511-240421 20-511-240396
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. MAb to Myeloperoxidase. Monoclonal Antibody to Human Myeloperoxidase (MPO)
Function:	Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN MPO catalyzes the production of hypohalous acids primarily hypochlorous acid in physiologic situations and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalytic Activity:	Donor + H2O2 = oxidized donor + 2 H2O.
Catalytic Activity:	Cl- + H2O2 = HOCl + 2 H2O. Cofactor: Binds 1 calcium ion per heterodimer. Cofactor: Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.
Subunit:	Tetramer of two light chains and two heavy chains.
Subcellular Location:	Lysosome.
Disease:	Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Similarity:	Belongs to the peroxidase family. XPO subfamily.

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Menge: 1 mg

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Lieferung vsl. bis 30.05.2024

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