FGF Receptor 1

ArtNr	20-511-240496
Hersteller	GENWAY
Menge	0,25 mg
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Clon	M5G10
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-68DD5A
Similar products	20-511-240496
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Genway ID:	GWB-68DD5A
Isotype:	IgG1
Clone:	M5G10Host Animal: Mouse
Immunogen:	Recombinant human ectodomain of FGFr1-beta expressed in E. coli beginning with proline 23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.
Specificity:	Reacts with both alpha (denatured) and beta isoforms. Epitope is within the sequence his241 and val267 between Ig loops II and III. Epitope is masked in undenatured FGFr1-alpha.
Type of Product:	Monoclonal Antibodies to Cytokines and Growth Factors
Concentration:	1. 5mg/ml (OD280)
Buffer:	PBS pH 7. 4Applications Notes :
Western Blotting:	1ug/ml recognizes 10ng recombinant bacterial baculoviral or native FGFr1. . Immunoprecipitation: native recombinant and ligand-labeled FGFr1. . Immunohistochemistry: paraffin-embedded human salivary gland tumors. . Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. MAb to FGF Receptor 1. Monoclonal Antibody to Fibroblast Growth Factor (FGF) Receptor 1
Function:	Receptor for basic fibroblast growth factor. A shorter form of the receptor could be a receptor for FGF1 (aFGF).
Catalytic Activity:	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit:	Interacts with SHB and KLB.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Similarity:	Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
Similarity:	Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Similarity:	Contains 1 protein kinase domain.

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Menge: 0,25 mg

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Lieferung vsl. bis 30.10.2025

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