Insulin

ArtNr	20-511-241012
Hersteller	GENWAY
Menge	0.1ml
Kategorie	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies ELISA Endocrine Regulation of Lipid Metabolism Immunoassay Primary Antibodies
Typ	Antibody
Applikationen	ELISA, RIA
Clon	3A6
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-EFD210
Similar products	20-511-241012
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Genway ID:	GWB-EFD210
Isotype:	IgG1. k
Clone:	3A6Host Animal: Mouse. Hybridization of X63-Ag8-653
Specificity:	Human insulin. Cross-reacts with human proinsulin bovine insulin (30%) and porcine insulin. No cross-reaction with free C-peptide.
Immunogen:	Purified human insulin.
Affinity Constant:	8. 0 x 108M-1
Type of Product:	Monoclonal Antibodies to Hormones and Steroids
Concentration:	Lot specificPreservatives: 0. 1% Sodium azide
Buffer:	PBS pH 7. 4Applications Notes : Detection of insulin in two-site enzyme immunoassay. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Recommended pair for sandwich immunoassay. Capture:20-511-241012 Detection: 20-511-241018
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. MAb to Insulin. Monoclonal Antibody to Human Insulin
Function:	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides amino acids and fatty acids. It accelerates glycolysis the pentose phosphate cycle and glycogen synthesis in liver.
Subunit:	Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Subcellular Location:	Secreted.
Disease:	Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]. Pharmaceutical: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
Similarity:	Belongs to the insulin family.

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