Hersteller |
GENWAY
|
Kategorie |
|
Typ |
Antibody |
Specific against |
other |
Clon |
OX-110 |
Applikationen |
FC |
Menge |
0.025 mg |
ArtNr |
20-783-310320 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Genway ID: |
GWB-2313A7 |
Specificity: |
CD200RNCBI |
Gene ID: |
57781 |
Specificity: |
CD200R |
Clone: |
OX-110 |
Immunogen: |
Fusion protein mCD200RCD4d3+4 |
Preparation: |
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
Buffer Solution: |
Phosphate buffered saline pH7. 4 |
|
Preservative Stabilisers: |
| 0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested |
Flow Cytometry: |
Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/). Suggested |
Dilution: |
Flow Cytometry - 1/10 |
Function: |
Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. |
Subunit: |
Interacts with Human herpesvirus 8 vOX2 protein. |
Subcellular Location: |
Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Subcellular Location: |
Isoform 4: Cell membrane; Single-pass type I membrane protein. |
Subcellular Location: |
Isoform 2: Secreted. |
Subcellular Location: |
Isoform 3: Secreted. |
Tissue Specificity: |
Expressed in granulocytes monocytes most T cells neutrophils basophils and a subset of NK NKT and B cells (at protein level). Expressed in bone marrow lymph nodes spleen lung liver spinal cord kidney. Expressed in monocyte-derived dendritic and mast cells. |
Ptm: |
The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform. |
Similarity: |
Belongs to the CD200R family. |
Similarity: |
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. |
Similarity: |
Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Wright. G. J. et al. (2003) Characterization of the CD200 Receptor family in mice and humans and their interactions with CD200. |
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