CD80


Hersteller	GENWAY
Kategorie	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Specific against	other
Clon	RM80
Applikationen	FC
Menge	25 TESTS
ArtNr	20-783-310493
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Genway ID:	GWB-5ABE0C
Specificity:	CD80NCBI
Gene ID:	12519
Specificity:	CD80
Clone:	RM80
Immunogen:	BCL1 cells expressing CD80
Fusion Partner:	Spleen cells from immunised SD rats were fused with cells of the P3U1 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)1%Bovine Serum Albumin Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (/). Suggested
Dilution:	Flow Cytometry - Neat
Function:	Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
Subunit:	Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Expressed on activated B-cells macrophages and dendritic cells.
Similarity:	Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Nuriya. S. et al. (1996) The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity. 2. Jin. L-P et al. (2004) Adoptive transfer of paternal antigen-hyporesponsive T cells induces maternal tolerance to the allogeneic fetus in abortion-prone matings. 3. Nakajima. A. et al. (1997) Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells. 4. Nozawa. K. et al. (2001) Preferential blockade of CD8+ T cell responses by administration of anti-CD137 ligand monoclonal antibody results in differential effect on development of murine acute and chronic graft-versus-host diseases.

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Menge: 25 TESTS

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Lieferung vsl. bis 30.05.2024

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