GROWTH HORMONE


ArtNr	20-783-310667
Hersteller	GENWAY
Menge	0.2 mg
Kategorie	Oncology Metabolism Diabetes Antibodies ELISA Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Applikationen	ELISA
Clon	GhB9
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-BC3858
Similar products	20-783-310667
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Genway ID:	GWB-BC3858
Specificity:	GROWTH HORMONENCBI
Gene ID:	2688
Specificity:	GROWTH HORMONE
Clone:	GhB9
Immunogen:	Purified recombinant human growth hormone
Fusion Partner:	Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8-653 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH 7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)
Function:	Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subunit:	Monomer dimer trimer tetramer and pentamer disulfide-linked or non-covalently associated in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.
Subcellular Location:	Secreted.
Disease:	Defects in GH1 are a cause of isolated growth hormone deficiency type IB (IGHD IB) [MIM:262400]; also known as pituitary dwarfism I. IGHD IB is an autosomal recessive deficiency of GH which causes short stature.
Disease:	Defects in GH1 are the cause of Kowarski syndrome [MIM:262650]; also known as pituitary dwarfism VI.
Disease:	Defects in GH1 are a cause of isolated growth hormone deficiency type II (IGHD II) [MIM:173100]. IGHD II is an autosomal dominant deficiency of GH which causes short stature.
Disease:	Defects in GH1 may be a cause of short stature [MIM:604271]. Short stature is defined by a subnormal rate of growth. Pharmaceutical: Available under the names Nutropin or Protropin (Genentech) Norditropin (Novo Nordisk) Genotropin (Pharmacia Upjohn) Humatrope (Eli Lilly) and Saizen or Serostim (Serono). Used for the treatment of growth hormone deficiency and for Turner\' s syndrome.
Miscellaneous:	Circulating GH shows a great heterogeneity due to alternative splicing differential post-translational modifications of monomeric forms oligomerization optional binding to 2 different GH-binding proteins and potentially proteolytic processing.
Similarity:	Belongs to the somatotropin/prolactin family.

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Menge: 0.2 mg

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Lieferung vsl. bis 30.10.2025