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UBIQUITIN

ArtNr 20-783-70447
Hersteller GENWAY
Menge 0.1 mg
Kategorie
Typ Antibody
Applikationen WB, FC, IHC, ELISA
Clon 1B4-UB
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-641C1B
Similar products 20-783-70447
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Genway ID:
GWB-641C1B
Specificity:
UBIQUITIN
Specificity:
UBIQUITIN
Clone:
1B4-UB
Immunogen:
Ubiquitin from bovine erythrocytes conjugated to bovine gamma globulin
Fusion Partner:
Spleen cells from immunised BALB/c mouse were fused with cells of the mouse PAI myeloma cell line.
Specificity Note:
This product recognises both human and bovine ubiquitin.
Immunohistology:
This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Histology: Human hypophysis
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Dilution:
Suggested
Dilution:
Flow Cytometry - 1/10 - 1/50Immunohistology - Frozen - 1/500 - 1/1000
Function:
Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions including maintenance of chromatin structure regulation of gene expression stress response ribosome biogenesis and DNA repair.
Subcellular Location:
Cytoplasm. Nucleus.
Ptm:
Several types of polymeric chains can be formed depending on the lysine used for the assembly.
Miscellaneous:
Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat here in human a Val. Some ubiquitin genes contain a single copy of ubiquitin fused to a ribosomal protein (either L40 or S27a).
Similarity:
Belongs to the ubiquitin family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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