THIOREDOXIN

GWB-4BD415

7295

2B1

This product recognises human thioredoxin a 12kD redox protein which has powerful protein disulphide oxidoreductase activity. Thioredoxin has been shown to be involved in various cellular processes including activation of the transcription factor NF-KB.

Western Blotting - 10ug/ml - 50ug/ml Summary: Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified including ribonuclease choriogonadotropins coagulation factors glucocorticoid receptor and insulin. Reduction of insulin is classically used as an activity test. [supplied by OMIM]. Summary: Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified including ribonuclease choriogonadotropins coagulation factors glucocorticoid receptor and insulin. Reduction of insulin is classically used as an activity test. [supplied by OMIM]. 1. Perkins. A. V. et al. (1995) Immunocytochemical localization of thioredoxin in human trophoblast and decidua.