p19


ArtNr	20-783-71349
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Oncology Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies By Organ Bladder Cancer
Typ	Antibody
Applikationen	WB, IP, IHC
Clon	DCS100. 1
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-C1E057
Similar products	20-783-71349
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Genway ID:	GWB-C1E057
Specificity:	p19NCBI
Gene ID:	1032
Specificity:	p19
Clone:	DCS100. 1
Immunogen:	Full length recombinant p19-His tagged
Specificity Note:	This product recognises human p19ink4d a 19kD tumour suppressor protein which is a specific inhibitor of cdk4/cdk6. p19ink4d is periodically expressed during the cell cycle. Maximum induction of p19ink4d occurs as cells enter S phase. * Clone DCS100. 1 co-precipitates cdk4/cdk6 in immunoprecipitation studies. Histology: Spleen
Preparation:	Purified IgG prepared by affinity chromatography on Protein G and A from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 08%Sodium Azide Summary: This protein is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit IL23R. Both IL23 and IL12 can activate the transcription activator STAT4 and stimulate the production of interferon-gamma (IFNG). In contrast to IL12 which acts mainly on naive CD4(+) T cells IL23 preferentially acts on memory CD4(+) T cells. Summary: This protein is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit IL23R. Both IL23 and IL12 can activate the transcription activator STAT4 and stimulate the production of interferon-gamma (IFNG). In contrast to IL12 which acts mainly on naive CD4(+) T cells IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq]. 1. Hirai. H. et al. (1995) Novel INK4 proteins. p19 and p18. are specific inhibitors of the cyclin D-Dependent kinases CDK4 and CDK6.

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