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Mouse Anti-Mouse NK1.1 (Ly-55)

Mouse Anti-Mouse NK1.1 (Ly-55)

ArtNr	20-787-275624
Hersteller	GENWAY
Menge	0.2 mg
Kategorie	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Bone Cancer
Typ	Antibody
Applikationen	FC
Clon	PK136
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-1ACBF2
Similar products	20-787-275624
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Genway ID:	GWB-1ACBF2
Isotype:	Mouse [(C3H x BALB/c)F1] IgG2a kappa
Clone:	PK136
Immunogen:	CE mouse spleen and bone marrow cells enriched for NK-1+ cells 1
Characterization:	To insure acceptable performance each batch of product is tested by flow cytometry to conform to characteristics of a standard reference reagent. Representative flow data are included with this product insert.
Specificity:	Mouse NK1. 1 alloantigen Mr 80-85 kDa (39 kDa under reducing conditions)NK1. 1 a member of the NKR-P1 family of cell surface receptors is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e. g. C57BL NZB). 1-4 10 NK1. 1 mediates cellular activation and differentiation and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice. 5-9
Working Dilution:	Flow Cytometry: 0. 5 ug/10^6 cells
Warning:	Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin eyes or clothing. Wear eye or face protection when handling. If skin or eye contact occurs wash with copious amounts of water. If ingested or inhaled contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Similarity:	Contains 1 C-type lectin domain. 1. Michie. S. A. P. R. Streeter E. C. Butcher and R. V. Rouse. 1995. Am. J. Pathol. 147:412. 2. Garni-Wagner B. A. A. Purohit P. A. Matthew M. Bennett and V. Kumar. 1993. J. Immunol. 151:60. 3. Koo G. C. F. J. Dumont M. Tutt J. Hackett Jr. and V. Kumar. 1996. J. Immunol. 137:3742. 4. Yokoyama W. M. and W. E. Seaman. 1993. Annu Rev. Immunol. 11:613. 5. Sentman C. L. V. Kumar G. Koo and M. Bennett. 1989. J. Immunol. 142:1847. 6. Yu Y. Y. L. V. Kumar and M. Bennett. 1992. Annu. Rev. Immuonol. 10:189. 7. Vicari A. P. and A. Zlotnik. 1996. Immunol. Today 17:71. 8. Lanier L. L. 1997. Immunity 6:371. 9. Sentman C. L. J. Hackett Jr. T. A. Moore M. M. Tutt M. Bennett and V. Kumar. 1989. Hybridoma 8:605. 10. Koo G. and J. Peppard. 1984. Hybridoma 3:301. 11. Reichlin A. and W. M. Yokoyama. 1998. Immunol. Cell Biol. 76:143. 12. Karlhofer F. M. and W. M. Yokoyama. 1991. J. Immunol. 146:3662. 13. Poulton L. D. M. J. Smyth C. G. Hawke P. Silveria D. Shepherd O. V. Naidenko D. I. Godfrey and A. G. Baxter. 2001. Int. Immunol. 13:887. 14. Routes J. M. J. C. Ryan S. Ryan and M. Nakamura. 2001. Int. Immunol. 13:1301.

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Menge: 0.2 mg

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