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Angiotensin II (4-8) Human

ArtNr 06-271-83072
Hersteller GENWAY
Menge 5 mg
Kategorie
Typ Peptides
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GWB-593701
Similar products 06-271-83072
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Genway ID:
GWB-593701
Sequence (One Letter Code):
YIHPF
Sequence:
{TYR} {ILE} {HIS} {PRO} {PHE}
Formula:
C35H45N7O7
Solubility:
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. AII(4-8) did not affect vertical activity of animals in electromagnetic motimeter. AII(4-8) influences central dopaminergic system. but unlike its parent peptide AII. AII(4-8) has no apparent effect on memory.
Function:
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Membrane; multi-pass membrane protein.
Tissue Specificity:
Liver lung adrenal and adrenocortical adenomas.
Ptm:
C-terminal Ser or Thr residues may be phosphorylated.
Similarity:
Belongs to the G-protein coupled receptor 1 family [view classification]. [1] Mauzy C. A. Hwang O. Egloff A. M. Wu L. H. Chung F. -Z. Cloning expression and characterization of a gene encoding the human angiotensin II type 1A receptor. [2] Furuta H. Guo D. F. Inagami T. Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor. [3] Bergsma D. J. Ellis C. Kumar C. Nuthalaganti P. Kersten H. Elshourbagy N. A. Griffin E. Stadel J. M. Aiyar N. Cloning and characterization of a human angiotensin II type 1 receptor. [4] Takayanagi R. Ohnaka K. Sakai Y. Nakao R. Yanase T. Haji M. Inagami T. Furuta H. Gou D. F. Nakamuta M. et al. Molecular cloning sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor. [5] Curnow K. M. Pascoe L. White P. C. Genetic analysis of the human type-1 angiotensin II receptor. [6] Konishi H. Kuroda S. Inada Y. Fujisawa Y. Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression. [7] Nawata H. Takayanagi R. Ohnaka K. Sakai Y. Imasaki K. Yanase T. Ikuyama S. Tanaka S. Ohe K. Type 1 angiotensin II receptors of adrenal tumors. [8] Ostermann E. Castanon M. J. Cloning and sequencing of a human cDNA encoding the angiotensin II receptor type 1. [9] Antonellis A. Rogus J. J. Pezzolesi M. G. Makita Y. Nam M. Doria A. Warram J. H. Krolewski A. S. Rapid identification of polymorphisms in genomic DNA: a high density SNP map of the type I angiotensin II receptor gene locus on chromosome 3q. [10] Kopatz S. A. Aronstam R. S. Sharma S. V. cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www. cdna. org).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 mg
Lieferbar: In stock
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