EBV-Induced G-Protein Coupled Receptor 2

GWB-F5DB95

Orphan receptor. Probable mediator of EBV effects on B lymphocytes or of normal lymphocyte functions.

B-lymphocyte cell lines.

Belongs to the G-protein coupled receptor 1 family [view classification]. Summary: This protein was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This protein is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown. [1] Suzuki Y. Yoshitomo-Nakagawa K. Maruyama K. Suyama A. and Sugano S. Construction and characterization of a full length-enriched and a 5' -end-enriched cDNA library. [2] Maruyama K. and Sugano S. et al. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. [3] Birkenbach M. Josefsen K. Yalamanchili R. Lenoir G. and Kieff E. et al. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. [4] Birkenbach M. P. Josefsen K. Yalamanchili R. R. Lenoir G. M. Kieff E. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. [5] Strausberg R. L. Feingold E. A. Grouse L. H. Derge J. G. Klausner R. D. Collins F. S. Wagner L. Shenmen C. M. Schuler G. D. Altschul S. F. et al. Generation and initial analysis of more than 15 000 full-length human and mouse cDNA sequences. Product Protocol: To see this product used in a peer reviewed journal click the following link:CXC Chemokine Receptor 4 Is a Cell Surface Receptor for Extracellular Ubiquitin