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SENP5 Antibody (C-term)

SENP5 Antibody (C-term)

ArtNr	ABC-AP1237a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SENP5, Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5
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Primary Accession	Q96HI0
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	SENP5 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its conjugatable mature form and deconjugation of SUMO2 and SUMO3 from targeted substrates. This protein has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. SENP5 is required for cell division.
Bio References	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB0660
Gene ID	205564
Gene Name	SENP5
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of SENP5 polyclonal antibody (Cat. #AP1237a) in Saos-2 cell lysate. SENP5 (Arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SENP5 Antibody (C-term) (Cat.#AP1237a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	Q6NXL6; Q8WP32
Predicted	Pr, M
Isotype	Rabbit Ig
Calculated MW	86693
Antigen Region	524-555
Antigen Source	HUMAN
Target/Specificity	This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 524-555 amino acids from the C-terminal region of human SENP5.
NCBI Accession	NP_689912.2

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