Stanniocalcin-2 (STC2) Antibody (N-term)

Synthetic Peptide

STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.

Polyclonal

8614

Purified Rabbit Polyclonal Antibody (Pab)

All lanes : Anti-Stanniocalcin-2 (STC2) Antibody (N-term) at 1:500 dilution
Lane 1: mouse skeletal muscle tissue lysate

Lysates/proteins at 20 µg per lane.

Secondary Goat Anti-Mouse IgG/A/M(H/L), Peroxidase conjugated at 1/2000 dilution.

Observed band size : 32kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:1000

WB

Western blot analysis of anti-STC2 Antibody (N-term) (Cat# AP1443a) in mouse kidney tissue lysates (35ug/lane). STC2(arrow) was detected using the purified polyclonal antibody.

1:1000

WB

Stanniocalcin-2 (STC2) Antibody (N-term) (Cat. #AP1443a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Stanniocalcin-2 (STC2) Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:50~100

Rabbit Ig

16-46

This Stanniocalcin-2 (STC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human Stanniocalcin-2 (STC2).