Vergleich

Phospho-PDX1(T11) Antibody

ArtNr ABC-AP3669a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen IF, Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations References for protein:
1.Nicolino,M., et.al., Diabetes 59 (3), 733-740 (2010)
2.Cai,J., et.al., J Mol Cell Biol 2 (1), 50-60 (2010)
References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704].
NCBI NP_000200.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Pancreas/duodenum homeobox protein 1,PDX-1,Glucose-sensitive factor,GSF,Insulin promoter factor 1,IPF-1,Insulin upstream factor 1,IUF-1,Islet/duodenum homeobox-1,IDX-1,Somatostatin-transactivating factor 1,STF-1,PDX1,IPF1,STF1
Similar products PDX-1, PDX1, STF1, GSF, IDX-1, IPF1, STF-1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, Pancreas/duodenum homeobox protein 1
Lieferbar
Manufacturer - Category
Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Developmental Biology; Metabolism; Signal Transduction; Phospho Antibodies
Manufacturer - Targets
This PDX1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1.
Bio Background
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB15204
Gene Name
PDX1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
M, Rat
Calculated Molecular Weight
30771
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
IF: 1:100
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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