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INA (alpha internexin) Antibody (Center)

INA (alpha internexin) Antibody (Center)

ArtNr	ABC-AP6284c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	INA, NEF5, Alpha-internexin, 66 kDa neurofilament protein, Neurofilament 5, NF-66, Neurofilament-66, Alpha-Inx
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Primary Accession	Q16352
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	INA is a class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Bio References	Armstrong, R.A., Eur. J. Neurol. 13 (5), 528-532 (2006) Suzuki, T., Eur. J. Neurosci. 21 (2), 339-350 (2005) Cairns, N.J., Am. J. Pathol. 164 (6), 2153-2161 (2004)
Clonality	Polyclonal
Clone/Animal Names	RB13854
Gene ID	9118
Gene Name	INA
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	All lanes : Anti-INA Antibody (Center) at 1:1000-2000 dilution Lane 1: Human brain tissue lysate Lane 2: U-87 MG whole cell lysate Lane 3: SH-SY5Y whole cell lysate Lane 4: Mouse liver tissue lysate Lane 5: Mouse brain tissue lysate Lane 6: Rat brain tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000-2000
Legend image 2	All lanes : Anti-INA Antibody (Center) at 1:2000 dilution Lane 1: Human brain tissue lysate Lane 2: Mouse brain tissue lysate Lane 3: Rat brain tissue lysate Lane 4: SH-SY5Y whole cell lysate Lane 5: Human liver tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:2000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with INA antibody (Center) (Cat.#AP6284c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Other Accession	P23565; P46660; Q08DH7
Predicted	B
Isotype	Rabbit IgG
Calculated MW	55391
Antigen Region	290-319
Antigen Source	HUMAN
Target/Specificity	This INA (alpha internexin) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the Central region of human INA (alpha internexin).
NCBI Accession	NP_116116.1

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