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FGF1 Antibody (N-term)

ArtNr ABC-AP6379a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, IF, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products FGF1, aFGF, ECGF, FGFA, FGF-1, Fibroblast growth factor 1, Acidic fibroblast growth factor, Heparin-binding growth factor 1, HBGF-1, Endothelial cell growth factor
Lieferbar
Primary Accession
P05230
Antigen Type
Synthetic Peptide
Application
WB, IF, IHC-P
Bio Background
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
Bio References
Fukushima, S., Int. J. Oncol. 32 (2), 467-473 (2008)
Riley, B.M.Am. J. Med. Genet. A 143 (24), 3228-3234 (2007)
Tomaszewski, M., Circulation 116 (17), 1915-1924 (2007)
Clonality
Polyclonal
Clone/Animal Names
RB14519
Gene ID
2246
Gene Name
FGF1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Confocal immunofluorescent analysis of FGF1 Antibody (N-term)(Cat#AP6379a) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Type image 1
IF
Dilution image 1
1:10~50
Legend image 2
Anti-FGF1 Antibody (N-term) at 1:1000 dilution + SH-SY5Y whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 17 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with FGF1 antibody (N-term) (Cat.#AP6379a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3
IHC-P
Dilution image 3
1:10~50
Other Accession
P20002
Predicted
Pig
Isotype
Rabbit Ig
Calculated MW
17460
Antigen Region
5-30
Antigen Source
HUMAN
Target/Specificity
This FGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-30 amino acids from the N-terminal region of human FGF1.
NCBI Accession
NP_000791.1; NP_001138364.1; NP_001138406.1; NP_001138407.1; NP_001244134.1; NP_001244136.1; NP_001244137.1; NP_001244138.1; NP_001244139.1; NP_149127.1; NP_149128.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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