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DJ-1 Antibody (N-term)

ArtNr ABC-AP6407a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Kim, R.H., et al., Cancer Cell 7(3):263-273 (2005). Shinbo, Y., et al., Int. J. Oncol. 26(3):641-648 (2005). Takahashi-Niki, K., et al., Biochem. Biophys. Res. Commun. 320(2):389-397 (2004). Hering, R., et al., Hum. Mutat. 24(4):321-329 (2004). Maraganore, D.M., et al., Neurology 63(3):550-553 (2004).
NCBI NP_001116849.1,NP_009193.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Protein DJ-1,34--,Oncogene DJ1,Parkinson disease protein 7,PARK7
Similar products PARK7, Protein DJ-1, Oncogene DJ1, Parkinson disease protein 7, 34--
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Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Inflammatory response; Autophagy; Mitochondrion; Stress response
Manufacturer - Targets
This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.
Bio Background
Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 4 years, slow progression and initial good response to levodopa.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB8160
Gene Name
PARK7
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Predicted Reactivity
B, Zf
Calculated Molecular Weight
19891
Antigen Source
HUMAN
Antigen Region
1-30
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
IF: 1:10~50
WB: 1:2000
WB: 1:2000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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