Vergleich

MLF1 Antibody (N-term)

ArtNr ABC-AP6716a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MLF1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
Lieferbar
Primary Accession
P58340
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Bio References
Li, Z.F., J. Neurol. Sci. 264 (1-2), 77-86 (2008)
Yoneda-Kato, N., EMBO J. 24 (9), 1739-1749 (2005)
Clonality
Polyclonal
Clone/Animal Names
RB18642
Gene ID
4291
Gene Name
MLF1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Legend image 1
Western blot analysis of MLF1 Antibody (N-term) (Cat. #AP6716a) in mouse heart tissue lysates (35ug/lane). MLF1 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Western blot analysis of MLF1 (arrow) using rabbit polyclonal MLF1 Antibody (N-term) (Cat. #AP6716a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MLF1 gene.
Type image 2
WB
Dilution image 2
1:1000
Isotype
Rabbit Ig
Calculated MW
30627
Antigen Region
35-62
Antigen Source
HUMAN
Target/Specificity
This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human MLF1.
NCBI Accession
NP_001123628.1; NP_001123629.1; NP_001182361.1; NP_001182362.1; NP_001182363.1; NP_071888.1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen