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AMPK gamma (PRKAG1) Antibody (Center)

AMPK gamma (PRKAG1) Antibody (Center)

ArtNr	ABC-AP7048c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Minokoshi, Y., et al., Nature 428(6982):569-574 (2004). Hamilton, S.R., et al., FEBS Lett. 500(3):163-168 (2001). Zidovetzki, R., et al., AIDS Res. Hum. Retroviruses 14(10):825-833 (1998). Reinton, N., et al., Genomics 49(2):290-297 (1998). Stapleton, D., et al., FEBS Lett. 409(3):452-456 (1997).
NCBI	NP_001193638.1,NP_001193639.1,NP_002724.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	5'-AMP-activated protein kinase subunit gamma-1,AMPK gamma1,AMPK subunit gamma-1,AMPKg,PRKAG1
Similar products	PRKAG1, 5'-AMP-activated protein kinase subunit gamma-1, AMPKg, AMPK subunit gamma-1, AMPK gamma1
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction
Manufacturer - Targets	This AMPK gamma (PRKAG1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-295 amino acids from the Central region of human AMPK gamma (PRKAG1).
Bio Background	PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3173
Gene Name	PRKAG1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B, Pig
Calculated Molecular Weight	37579
Antigen Source	HUMAN
Antigen Region	265-295
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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