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STK11 (LKB1) Antibody (C-term)

STK11 (LKB1) Antibody (C-term)

ArtNr	ABC-AP7239B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	STK11, LKB1, Serine/threonine-protein kinase STK11, PJS, Liver kinase B1, Renal carcinoma antigen NY-REN-19, hLKB1
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Primary Accession	Q15831
Antigen Type	Synthetic Peptide
Application	IHC-P
Bio Background	STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Bio References	Mart, et al., J. Biotechnol. 115(1):23-34 (2005). Shaw, R.J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(10):3329-3335 (2004). Suzuki, A., et al., Biochem. Biophys. Res. Commun. 324(3):986-992 (2004). Hearle, N., et al., Genes Chromosomes Cancer 41(2):163-169 (2004). Corradetti, M.N., et al., Genes Dev. 18(13):1533-1538 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB3549/3550
Gene ID	6794
Gene Name	STK11 (HGNC:11389)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 1	IHC-P
Dilution image 1	1:50~100
Isotype	Rabbit Ig
Calculated MW	48636
Antigen Region	387-417
Antigen Source	HUMAN
Target/Specificity	This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human STK11 (LKB1).
NCBI Accession	NP_000446.1

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Menge: 400 ul

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