Vergleich

HRG Antibody (N-term)

ArtNr ABC-AP7327a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products HRG, HPRG, Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein
Lieferbar
Primary Accession
P04196
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Bio References
Vanwildemeersch, M., Olsson, A.K. J. Biol. Chem. 281 (15), 10298-10304 (2006)
Jones, A.L., Poon, I.K. J. Biol. Chem. 280 (42), 35733-35741 (2005)
Hennis, B.C. and Kluft, C. Nucleic Acids Res. 19 (15), 4311 (1991)
Clonality
Polyclonal
Clone/Animal Names
RB18729
Gene ID
3273
Gene Name
HRG
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Anti-HRG Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 60 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
HRG Antibody (N-term) (RB18729) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HRG Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:50~100
Isotype
Rabbit Ig
Calculated MW
59578
Antigen Region
13-42
Antigen Source
HUMAN
Target/Specificity
This HRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human HRG.
NCBI Accession
NP_000403.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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