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GIT1 Antibody (Center)

GIT1 Antibody (Center)

ArtNr	ABC-AP7416c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GIT1, CAT1, CAT-1, G protein-coupled receptor kinase-interactor 1, ARF GAP GIT1, ARF GTPase-activating protein GIT1, Cool-associated and tyrosine-phosphorylated protein 1, GRK-interacting protein 1
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Primary Accession	Q9Y2X7
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
Bio References	Sato, H., Biochem. Biophys. Res. Commun. 368 (1), 157-161 (2008) Jones, N.P., Mol. Cell. Biol. 27 (16), 5790-5805 (2007) Schmalzigaug, R., Cell. Signal. 19 (8), 1733-1744 (2007) Stockton, R., Mol. Biol. Cell 18 (6), 2346-2355 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB15673
Gene ID	28964
Gene Name	GIT1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-GIT1 Antibody (Center) at 1:2000 dilution Lane 1: U-2OS whole cell lysate Lane 2: HUVEC whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 84 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Legend image 2	GIT1 Antibody (Center) (Cat. #AP7416c) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GIT1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q9Z272; Q68FF6
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	84341
Antigen Region	485-512
Antigen Source	HUMAN
Target/Specificity	This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 485-512 amino acids from the Central region of human GIT1.
NCBI Accession	NP_001078923.1; NP_054749.2

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Menge: 400 ul

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