CAMK2A Antibody (C-term E370)

Synthetic Peptide

CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.

Polyclonal

815

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of anti-CAMK2A Antibody (C-term E370) (Cat.#AP7418b) in 293 cell line lysates (35ug/lane). CAMK2A(arrow) was detected using the purified Pab.

1:1000

WB

Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) (Cat.#AP7418b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

1:10~50

M, Rat

54088

HUMAN

NP_741960.1