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CDK10 Antibody (N-term)

CDK10 Antibody (N-term)

ArtNr	ABC-AP7516A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CDK10, Cyclin-dependent kinase 10, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE
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Primary Accession	Q15131
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.
Bio References	Crawford, J., et al., Genomics 56(1):90-97 (1999). Brambilla, R., et al., Oncogene 9(10):3037-3041 (1994). Grana, X., et al., Oncogene 9(7):2097-2103 (1994). Morgan, D. O. Annu. Rev. Cell Dev. Biol. 13, 261 (1997) Sherr, C. Science 274:1672 (1996) Kamb A. TIG 11:136 (1995) Zhang, H. et al, Cell 82, 915 (1995) Parge, HE. et al., Science 262, 387 (1993) Hershko, A. et al., Ann. Rev. Biochem. 61, 761 (1992) Peters, JM. Curr. Biol. 10, 759 (1998) Skowyra, D. etal., Cell 91, 209 (1997) Ganoth D. et al., Nature Cell Biol. 3, 321-324 (2001)
Clonality	Polyclonal
Clone/Animal Names	RB3172
Gene ID	8558
Gene Name	CDK10
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of CDK10 antibody (N-term) (Cat. #AP7516a) pre-incubated with (Lane1) and without (Lane 2) blocking peptide (Cat. #BP7516a) in A375 cell line lysate. CDK10 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q3UMM4
Predicted	M
Isotype	Rabbit Ig
Calculated MW	41038
Antigen Region	1-32
Antigen Source	HUMAN
Target/Specificity	This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.
NCBI Accession	NP_001092003.2; NP_001153839.1; NP_443713.2; NP_443714.3

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Menge: 400 ul

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