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ALK Antibody (N-term)

ALK Antibody (N-term)

ArtNr	ABC-AP7600a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Primary Antibodies Astrocytoma
Typ	Antibody Polyclonal
Applikationen	IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Morris, S.W., et al., Oncogene 14(18):2175-2188 (1997). Iwahara, T., et al., Oncogene 14(4):439-449 (1997). Morris, S.W., et al., Science 263(5151):1281-1284 (1994). Morris, S.W., et al., Oncogene 15, 2883-2883 (1997).
NCBI	NP_004295.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,ALK
Similar products	ALK, ALK tyrosine kinase receptor, CD246, Anaplastic lymphoma kinase
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Manufacturer - Category	Primary Antibodies; Cancer; Neuroscience; Anti-Kinome Antibodies
Manufacturer - Targets	This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~43 amino acids from the N-terminal region of human ALK.
Bio Background	ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2; 5)(p23; q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB1511-1512
Gene Name	ALK {ECO:0000303\|PubMed:9174053, ECO:0000312\|HGNC:HGNC:427}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	176442
Antigen Source	HUMAN
Antigen Region	14-43
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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