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ERBB2 Antibody(N-term)

ArtNr ABC-AP7629a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Ehsani, A., et al., Genomics 15(2):426-429 (1993).
Yamamoto, T., et al., Nature 319(6050):230-234 (1986).
Coussens, L., et al., Science 230(4730):1132-1139 (1985).
Semba, K., et al., Proc. Natl. Acad. Sci. U.S.A. 82(19):6497-6501 (1985).
NCBI NP_001005862.1,NP_004439.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Receptor tyrosine-protein kinase erbB-2,Metastatic lymph node gene 19 protein,MLN 19,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface receptor HER2,p185erbB2,CD340,ERBB2,HER2,MLN19,NEU,NGL
Similar products ERBB2, Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, Tyrosine kinase-type cell surface receptor HER2, MLN 19, HER2, NEU, NGL, MLN19, Metastatic lymph node gene 19 protein, CD340
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies
Manufacturer - Targets
This ERBB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human ERBB2.
Bio Background
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP3 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An Interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB01464
Gene Name
ERBB2
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
M, Rat
Calculated Molecular Weight
137910
Antigen Source
HUMAN
Antigen Region
21-52
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
IHC-P: 1:50~100
IHC-P: 1:50~100
FC: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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