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PDGFRA Antibody (Y754)

PDGFRA Antibody (Y754)

ArtNr	ABC-AP7666J
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Wilczynski, S.P., et al., Hum. Pathol. 36(3):242-249 (2005). Hiwatari, M., et al., Leukemia 19(3):476-477 (2005). Debiec-Rychter, M., et al., Gastroenterology 128(2):270-279 (2005). Sakurai, S., et al., Hum. Pathol. 35(10):1223-1230 (2004). Subramanian, S., et al., Oncogene 23(47):7780-7790 (2004).
NCBI	NP_006197.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Platelet-derived growth factor receptor alpha,PDGF-R-alpha,PDGFR-alpha,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140a antigen,Platelet-derived growth factor alpha receptor,Platelet-derived growth factor receptor 2,PDGFR-2,CD140a,PDGFRA,PDGFR2,RHEPDGFRA
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Signal Transduction; Anti-Kinome Antibodies; Viral process; Host-virus interaction
Manufacturer - Targets	This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 732-761 amino acids from human PDGFRA.
Bio Background	PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB11213
Gene Name	PDGFRA
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	122670
Antigen Source	HUMAN
Antigen Region	732-761
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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