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RET Antibody (N-term Q28)

ArtNr ABC-AP7669c
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Da Silva, A.M., et al., J. Clin. Endocrinol. Metab. 88(11):5438-5443 (2003).
McWhinney, S.R., et al., J. Clin. Endocrinol. Metab. 88(10):4911-4916 (2003).
D'Alessio, A., et al., Endocrinology 144(10):4298-4305 (2003).
Soares, P., et al., Oncogene 22(29):4578-4580 (2003).
Punales, M.K., et al., J. Clin. Endocrinol. Metab. 88(6):2644-2649 (2003).
NCBI NP_065681.1,NP_066124.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,Soluble RET kinase fragment,Extracellular cell-membrane anchored RET cadherin 120 kDa fragment,RET,CDHF12,CDHR16,PTC,RET51
Similar products RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies
Manufacturer - Targets
This RET antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-44 amino acids from the N-terminal region of human RET.
Bio Background
RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB01516
Gene Name
RET {ECO:0000303|PubMed:2660074, ECO:0000312|HGNC:HGNC:9967}
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
124319
Antigen Source
HUMAN
Antigen Region
13-44
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
FC: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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