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ACVRL1 Antibody (C-term)

ACVRL1 Antibody (C-term)

ArtNr	ABC-AP7807b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Berg, J.N., et al., Am. J. Hum. Genet. 61(1):60-67 (1997). Johnson, D.W., et al., Nat. Genet. 13(2):189-195 (1996). ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993). Attisano, L., et al., Cell 75(4):671-680 (1993).
NCBI	NP_000011.2,NP_001070869.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase receptor R3,SKR3,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,ACVRL1,ACVRLK1,ALK1
Similar products	ACVRL1, TGF-B superfamily receptor type I, ACVRLK1, ALK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, ALK-1, SKR3, TSR-I
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction
Manufacturer - Targets	This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human ACVRL1.
Bio Background	ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB03737
Gene Name	ACVRL1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	56124
Antigen Source	HUMAN
Antigen Region	474-503
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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