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B-RAF Antibody (S445)

ArtNr ABC-AP7810f
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Hingorani, S.R., et al., Cancer Res. 63(17):5198-5202 (2003).
Lee, J.W., et al., Br. J. Cancer 89(10):1958-1960 (2003).
Davies, H., et al., Nature 417(6892):949-954 (2002).
Naoki, K., et al., Cancer Res. 62(23):7001-7003 (2002).
Stephens, R.M., et al., Mol. Cell. Biol. 12(9):3733-3742 (1992).
NCBI NP_004324.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein kinase B-raf,Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1,BRAF,BRAF1,RAFB1
Similar products BRAF, p94, BRAF1, RAFB1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, v-Raf murine sarcoma viral oncogene homolog B1
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Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Signal Transduction; T cell activation; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling
Manufacturer - Targets
This B-RAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-453 amino acids from human B-RAF.
Bio Background
BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB10940, RB17180
Gene Name
BRAF
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
C, M
Calculated Molecular Weight
84437
Antigen Source
HUMAN
Antigen Region
424-453
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
IF: 1:10~50
IF: 1:25
WB: 1:1000
WB: 1:2000
WB: 1:2000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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