CYP17A1 Antibody (Center)

Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction; Catalog Updated

CYP17A1 is a member of the cytochrome P45 superfamily of enzymes. The cytochrome P45 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 2-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 2-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

RB16932

Purified Rabbit Polyclonal Antibody (Pab)

Pr

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Synthetic Peptide