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MEK2 (MAP2K2) Antibody (N-term)

ArtNr ABC-AP7961a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations Burroughs, K.D., et al., Mol. Cancer Res. 1(4):312-322 (2003).
Tran, H., et al., Mol. Cell. Biol. 23(20):7177-7188 (2003).
Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003).
Li, Y., et al., J. Biol. Chem. 278(16):13663-13671 (2003).
Liu, X., et al., J. Biol. Chem. 277(42):39312-39319 (2002).
NCBI NP_109587.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Dual specificity mitogen-activated protein kinase kinase 2,MAP kinase kinase 2,MAPKK 2,ERK activator kinase 2,MAPK/ERK kinase 2,MEK 2,MAP2K2,MEK2,MKK2,PRKMK2
Similar products MAP2K2, MEK2, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2, MKK2, PRKMK2, MAP kinase kinase 2, MAPKK 2, MEK 2
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Manufacturer - Category
Crown Antibodies; Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies; Toll receptor signaling; Toll-Like receptor signaling; B cell receptor signaling; T cell activation; T cell receptor signaling
Manufacturer - Targets
This MEK2 (MAP2K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MEK2 (MAP2K2).
Bio Background
MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB3595
Gene Name
MAP2K2
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M, Rat
Calculated Molecular Weight
44424
Antigen Source
HUMAN
Antigen Region
1-30
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
IF: 1:10~50
WB: 1:1000
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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