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PIK3R1 Antibody (Y580)

PIK3R1 Antibody (Y580)

ArtNr	ABC-AP8023f
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha
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Primary Accession	P27986
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.
Bio References	Kobayashi, H., et al., J. Biol. Chem. 279(8):6371-6379 (2004). Liu, H., et al., J. Cell Biol. 164(4):603-612 (2004). Sun, M., et al., J. Biol. Chem. 278(44):42992-43000 (2003). Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003). Lee, H.Y., et al., J. Biol. Chem. 278(26):23630-23638 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB13326
Gene ID	5295
Gene Name	PIK3R1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of PIK3R1 (arrow) using rabbit polyclonal PIK3R1 Antibody (Y580) (Cat.#AP8023f). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R1 gene (Lane 2) (Origene Technologies).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PIK3R1-pY580, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q63787; P26450; P23727; Q8UUU2
Predicted	X, B, M, Rat
Isotype	Rabbit Ig
Calculated MW	83598
Antigen Region	558-587
Antigen Source	HUMAN
Target/Specificity	This PIK3R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from human PIK3R1.
NCBI Accession	NP_001229395.1; NP_852556.2; NP_852664.1; NP_852665.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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