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BUBR1 (BUB1B) Antibody (N-term)

BUBR1 (BUB1B) Antibody (N-term)

ArtNr	ABC-AP8059a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Lung Cancer Skin Cancer Colorectal Cancer Breast Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Cahill, D.P., et al., Genomics 58(2):181-187 (1999). Davenport, J.W., et al., Genomics 55(1):113-117 (1999). Chan, G.K., et al., J. Cell Biol. 143(1):49-63 (1998). Cahill, D.P., et al., Nature 392(6673):300-303 (1998). Taylor, S.S., et al., J. Cell Biol. 142(1):1-11 (1998).
NCBI	NP_001202.4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta,MAD3/BUB1-related protein kinase,hBUBR1,Mitotic checkpoint kinase MAD3L,Protein SSK1,BUB1B,BUBR1,MAD3L,SSK1
Similar products	BUB1B, BUBR1, MAD3L, SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, MAD3/BUB1-related protein kinase, Mitotic checkpoint kinase MAD3L, Protein SSK1, hBUBR1
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Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology
Manufacturer - Targets	This BUBR1 (BUB1B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human BUBR1 (BUB1B).
Bio Background	BUB1B, a member of the Ser/Thr protein kinase family, is a probable component of the mitotic checkpoint that delays anaphase until all chromosomes are properly attached to the mitotic spindle. It can interact with BUB3, CENP-F, CENP-E and mitosin, and can be localized to nuclear kinetochores. This protein is highly expressed in thymus and spleen. The CD1 domain directs kinetochore localization and binding to BUB3. The protein possesses a cyclin destruction box sequence, which targets protein for rapid degradation by ubiquitin-dependent proteolysis during the transition from mitosis to interphase. Defects in BUB1B are associated with tumor formation.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB03121-03122
Gene Name	BUB1B
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	119545
Antigen Source	HUMAN
Antigen Region	3-33
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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