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PACSIN2 Antibody (C-term)

PACSIN2 Antibody (C-term)

ArtNr	ABC-AP8088b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PACSIN2, Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II
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Primary Accession	Q9UNF0
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.
Bio References	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Wiemann, S., et al., Genome Res. 11(3):422-435 (2001). Ritter, B., et al., FEBS Lett. 454(3):356-362 (1999). Dunham, I., et al., Nature 402(6761):489-495 (1999).
Clonality	Polyclonal
Clone/Animal Names	RB3584
Gene ID	11252
Gene Name	PACSIN2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	PACSIN2 Antibody (S357) (Cat.# AP8088b) western blot analysis in Daudi, HL-60 cell line and mouse brain, rat heart lysates (35ug/lane).This demonstrates the PACSIN2 antibody detected the PACSIN2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Immunohistochemical analysis of paraffin-embedded H. stomach section using PACSIN2 Antibody (C-term)(Cat#AP8088b). AP8088b was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Type image 2	IHC-P
Dilution image 2	1:25
Legend image 3	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 3	IHC-P
Dilution image 3	1:50~100
Isotype	Rabbit Ig
Calculated MW	55739
Antigen Region	342-371
Antigen Source	HUMAN
Target/Specificity	This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human PACSIN2.
NCBI Accession	NP_001171899.1; NP_001171900.1; NP_009160.2

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