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GSK3 beta (GSK3B) Antibody (N-term)

GSK3 beta (GSK3B) Antibody (N-term)

ArtNr	ABC-AP8121a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Dajani, R., et al., Cell 105(6):721-732 (2001). Lau, K.F., et al., Genomics 60(2):121-128 (1999). Rhoads, A.R., et al., Mol. Psychiatry 4(5):437-442 (1999). Delcommenne, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11211-11216 (1998).
NCBI	NP_001139628.1,NP_002084.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Glycogen synthase kinase-3 beta,GSK-3 beta,Serine/threonine-protein kinase GSK3B,GSK3B
Similar products	GSK3B, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B, GSK-3 beta
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Developmental Biology; Metabolism; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies; B cell receptor signaling; T cell receptor signaling; Chemokine signaling; Interleukin signaling
Manufacturer - Targets	This GSK3 beta (GSK3B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human GSK3 beta (GSK3B).
Bio Background	GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB03816
Gene Name	GSK3B
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	46744
Antigen Source	HUMAN
Antigen Region	4-34
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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