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Fructose 6 Phosphate Kinase Antibody (N-term)

Fructose 6 Phosphate Kinase Antibody (N-term)

ArtNr	ABC-AP8137a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PFKM, PFKX, Phosphofructo-1-kinase isozyme A, PFK-A, ATP-dependent 6-phosphofructokinase, PFK-M, ATP-PFK {ECO:0000255\|HAMAP-Rule:MF_03184}, 27111 {ECO:0000255\|HAMAP-Rule:MF_03184}, Phosphohexokinase {ECO:0000255\|HAMAP-Rule:MF_03184}, muscle type {ECO:0000255\|HAMAP-Rule:MF_03184}, 6-phosphofructokinase type A
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Primary Accession	P08237
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1, 6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.
Bio References	Howard, T.D., et al., Genomics 34(1):122-127 (1996). Vasconcelos, O., et al., Proc. Natl. Acad. Sci. U.S.A. 92(22):10322-10326 (1995). Raben, N., et al., J. Biol. Chem. 268(7):4963-4967 (1993). Yamasaki, T., et al., Gene 104(2):277-282 (1991). Sharma, P.M., et al., J. Biol. Chem. 265(16):9006-9010 (1990).
Clonality	Polyclonal
Clone/Animal Names	RB3905
Gene ID	5213
Gene Name	PFKM
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysate from human skeletal muscle tissue lysate, using PFKM Antibody （S137）(Cat. #AP8137a). AP8137a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	85183
Antigen Region	122-151
Antigen Source	HUMAN
Target/Specificity	This Fructose 6 Phosphate Kinase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the N-terminal region of human Fructose 6 Phosphate Kinase.
NCBI Accession	NP_000280.1; NP_001160158.1; NP_001160159.1; NP_001160160.1

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Menge: 400 ul

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