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FGF4 Antibody (C-term)

FGF4 Antibody (C-term)

ArtNr	ABC-AP8149B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FGF4, HSTF1, HST, KS3, Fibroblast growth factor 4, Heparin secretory-transforming protein 1, Heparin-binding growth factor 4, Transforming protein KS3, FGF-4, HST-1, HBGF-4, HSTF-1
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Primary Accession	P08620
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The gene for FGF4 was identified by its oncogenic transforming activity. The gene for FGF4 and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Bio References	Yamamoto, H., et al., Oncogene 21(6):899-908 (2002). Koh, K.R., et al., Leuk. Res. 26(10):933-938 (2002). Sieuwerts, A.M., et al., Thromb. Haemost. 87(4):674-683 (2002). Lopez-Sanchez, C., et al., Cell Tissue Res. 309(2):237-249 (2002). Galland, F., et al., Cytogenet. Cell Genet. 60(2):114-116 (1992).
Clonality	Polyclonal
Clone/Animal Names	RB4041
Gene ID	2249
Gene Name	FGF4
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-FGF4 Antibody (C-term) (Cat.#AP8149b) in CEM cell line lysates (35ug/lane). FGF4 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with FGF4 Antibody (C-term) (Cat.#AP8149b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Isotype	Rabbit Ig
Calculated MW	22048
Antigen Region	168-198
Antigen Source	HUMAN
Target/Specificity	This FGF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the C-terminal region of human FGF4.
NCBI Accession	NP_001998.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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