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Urokinase (PLAU) Antibody (N-term)

Urokinase (PLAU) Antibody (N-term)

ArtNr	ABC-AP8161a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies By Organ Breast Cancer
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Sperl, S., et al., Proc. Natl. Acad. Sci. U.S.A. 97(10):5113-5118 (2000). Turkmen, B., et al., Electrophoresis 18(5):686-689 (1997). Conne, B., et al., Thromb. Haemost. 77(3):434-435 (1997). Yoshimoto, M., et al., Biochim. Biophys. Acta 1293(1):83-89 (1996).
NCBI	NP_001138503.1,NP_002649.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Urokinase-type plasminogen activator,U-plasminogen activator,uPA,Urokinase-type plasminogen activator long chain A,Urokinase-type plasminogen activator short chain A,Urokinase-type plasminogen activator chain B,PLAU
Similar products	uPA, PLAU, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B, U-plasminogen activator
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Neuroscience
Manufacturer - Targets	This Urokinase (PLAU) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human Urokinase (PLAU).
Bio Background	PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-\|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB04087
Gene Name	PLAU
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	48523
Antigen Source	HUMAN
Antigen Region	60-90
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:1000 IHC-P: 1:10~50 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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