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PP2A alpha Antibody (N-term)

PP2A alpha Antibody (N-term)

ArtNr	ABC-AP8462a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PPP2CA, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Replication protein C, PP2A-alpha, RP-C
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Primary Accession	P67775
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	PPP2CA/B represents the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
Bio References	Gergs, U., et al., J. Biol. Chem. 279(39):40827-40834 (2004). Prickett, T.D., et al., J. Biol. Chem. 279(37):38912-38920 (2004). Scott, G.K., et al., EMBO J. 22(23):6234-6244 (2003). Rao, R.K., et al., Biochem. Biophys. Res. Commun. 293(1):610-616 (2002). Avdi, N.J., et al., J. Biol. Chem. 277(43):40687-40696 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB05998
Gene ID	5515
Gene Name	PPP2CA
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-hPPP2CA/B Antibody (N-term) (Cat.#AP8462a) in A2058 cell line lysates (35ug/lane). PPP2CA/B (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	P67777; P67776; P67774
Predicted	B, Pig, Rb
Isotype	Rabbit Ig
Calculated MW	35594
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This PP2A alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PP2A alpha.
NCBI Accession	NP_002706.1

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Menge: 400 ul

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