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LTA Antibody (Center)

LTA Antibody (Center)

ArtNr	ABC-AP8509c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TNF-beta, LTA, Lymphotoxin-alpha, LT-alpha, Tumor necrosis factor ligand superfamily member 1, TNFB, TNFSF1
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Primary Accession	P01374
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	LTA, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
Bio References	Buonaguro, L., et.al., J. Virol. 66 (12), 7159-7167 (1992) Fukushima, K., et.al., Arch. Biochem. Biophys. 304 (1), 144-153 (1993)
Clonality	Polyclonal
Clone/Animal Names	RB21239
Gene ID	4049
Gene Name	LTA
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of LTA Antibody (Center) (Cat. #AP8509c) in MDA-MB231 cell line lysates (35ug/lane). LTA (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with LTA Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Flow cytometric analysis of HepG2 cells using LTA Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	22297
Antigen Region	46-72
Antigen Source	HUMAN
Target/Specificity	This LTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the Central region of human LTA.
NCBI Accession	NP_000586.2; NP_001153212.1

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Menge: 400 ul

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