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VPS26A Antibody (Center)

VPS26A Antibody (Center)

ArtNr	ABC-AP8722C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	VPS26A, VPS26, Vacuolar protein sorting-associated protein 26A, Vesicle protein sorting 26A, hVPS26
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Primary Accession	O75436
Antigen Type	Synthetic Peptide
Application	FC, WB, IHC-P
Bio Background	VPS26A is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.
Bio References	Haft, C.R., et.al., Mol. Biol. Cell 11 (12), 4105-4116 (2000) Reddy, J.V.et.al., Mol. Biol. Cell 12 (10), 3242-3256 (2001)
Clonality	Polyclonal
Clone/Animal Names	RB22339
Gene ID	9559
Gene Name	VPS26A {ECO:0000303\|PubMed:30213940, ECO:0000312\|HGNC:HGNC:12711}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of VPS26A Antibody (Center) (Cat. #AP8722c) in HepG2 cell line lysates (35ug/lane). VPS26A (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VPS26A Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	VPS26A Antibody (Center) (Cat. #AP8722c) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	O01258; Q6AY86; P40336; Q6TNP8; Q0VD53; Q6DFU4; Q6IRD0
Predicted	X, B, Zf, M, Rat, E
Isotype	Rabbit Ig
Calculated MW	38170
Antigen Region	263-291
Antigen Source	HUMAN
Target/Specificity	This VPS26A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the Central region of human VPS26A.
NCBI Accession	NP_001030337.1; NP_004887.2

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ABC-AP8722C-datasheet.pdf

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Menge: 400 ul

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