IL10 Antibody (Center)

Primary Antibodies; Cancer; Immunology; Signal Transduction; T cell receptor signaling; Cytokine; Jak-STAT signaling KEGG; Allograft rejection; Intestinal immune network for IgA production

The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

RB21234

Affinity Purified Rabbit Polyclonal Antibody (Pab)

EBV, Pr

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide