OPRM1 Antibody (Center)

Synthetic Peptide

OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1; MIM 165196), and delta, each with a distinct pharmacologic profile.

Polyclonal

4988

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Anti-OPRM1 Antibody (Center) at 1:500 dilution + MDA-MB-231 whole cell lysate


Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 44 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:500

WB

OPRM1 Antibody (Center) (AP9130c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OPRM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

1:10~50

FC

P33535; Q95247; P42866; Q95M54

Rabbit Ig

161-187

This OPRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human OPRM1.